Giant Microbes Plush - Bone Cell (Osteocyte)
These Giant Microbes Dolls are a Million times their Actual Size! GIANT microbes are health and science products for humorous, educational, collectible, and Smart fun! Products include printed cards with fun fascinating facts. Unique gifts for students, scientists, teachers, health professionals & anyone with a healthy sense of humor!
All About Bone Cell (Osteocyte)
Toe bone connected to the foot bone, the foot bone connected to the funny bone! Learn about how bone cells regulate minerals in our bodies.
FACTS: Your bones are made primarily of an intricate edifice of mineralized tissue laid down by bone cells like a coral reef.
At first, the work is exciting and productive, as young cuboidal osteoblasts dutifully secrete the osteoid tissue that forms the bone matrix. Unfortunately, as the bone is constructed, these cells soon find themselves imprisoned in their own handiwork, buried alive!
In order to survive, these now mature osteocytes occupy little spaces called lacunae and reach out desperately to nearby cells with thin extensions (or cytoplasmic processes) into little channels (or canaliculi) in the bone. When they make contact, they form a living network inside the bone that can exchange nutrients and waste. They can also communicate about which parts of the bone are being stressed and need to be strengthened – as well as determine which parts should be left to decay.
This may create a glimmer of hope: as osteoclasts begin resorbing the bone matrix, the material covering the osteocytes is reduced. However, as bone stresses are constantly shifting, bones are typically remade, strengthening them and dooming the osteocytes to their fate.
Unfortunately, under certain circumstances, the resorption rate of the osteoclasts exceeds the bone-formation rate of the osteoblasts, which can result in osteoporosis. This general weakening of the bones is of particular concern to women when their estrogen levels drop after menopause (though the reduction of testosterone levels in men can also provoke increased osteoclast activity). In severe cases, bones can become so weakened that they fracture easily. Fortunately, lifestyle changes, dietary supplements, and medication can help prevent sufferers from becoming trapped by the condition.
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This was sent to a brave relative going through some medical stuff. It was greatly received.
I recently received these and very quickly given that they were shipped to the UK. The items are high quality and as described. We are particularly fond of Douglas the lucky pickle. Thanks very much for the smooth service
Arrived in great condition
Arrived in great condition - no problems
Arrived in great condition
This large plush arrived hard as a rock and must’ve been exposed to the frigid cold at the time . I emailed customer service and received reply wn 24 hrs w instruction to knead it heavily which worked !
This large plush arrived hard as a rock and I’d never seen that before . I emailed customer service and got a response in 24 hrs saying to knead it to soften the toy . It took a heavy hand and a lot of work but it finally softened
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I was hoping there would be more miniatures of the original run of Hot Wheels cars from 1968. I will get them all regardless.
Very nice little replica.
Neat little toys. Front end loader is next.
Once I fill it with the world's smallest Hot Wheels cars, I will buy another and fill it up, too!
I really love this set! They are absolutely adorable. Thanks for the quick shipping and the discount coupon. I will be back for more shopping.
My 5 year old sun he love it so fun